Countdown to the introduction of a norovirus vaccine

Public release date: 17-Feb-2012
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Contact: Joseph Caspermeyer
Joseph.Caspermeyer@asu.edu
Arizona State University

Noroviruses are believed to make up half of all food-borne disease outbreaks in the United States, causing incapacitating (and often violent) stomach flu. These notorious human pathogens are responsible for 90 percent of epidemic nonbacterial outbreaks of gastroenteritis around the world.

On Friday, February 17, 2012 at 10:00 a.m., Charles Arntzen, ASU Regents' professor, and professor in the Center for Infectious Diseases and Vaccinology at the Biodesign Institute will deliver a lecture entitled Countdown to the Introduction of a Norovirus Vaccine. The talk will take place during the American Association for the Advancement of Science's annual meeting in Vancouver, BC.

Arntzen's lecture is part of a special topical seminar: NorovirusThe Modern Scourge of Food and Family.

The seminar title is well chosennoroviruses are extremely contagious, readily passing from person to person, particularly among those living in the closed quarters of dormitories, nursing homes, child care centers, military bases, and cruise ships. Infections can result from contact with virus particles dispersed in the air or from the ingestion of even tiny quantities of contaminated food. Further, even vigorous hand washing or the use of alcohol wipes or gels may be ineffective in combating norovirus transmission. Noroviruses can persist in a transmissible state for days or weeks even in those who are asymptomatic or are recovering from the disease.

Arntzen will speak about the prospects for a successful vaccine to prevent norovirus infection, based on Virus-Like Particles (VLPs), which are able to mimic actual noroviruses, stimulating a robust immune response, without producing disease symptoms. Due to the frequent mutation of noroviruses, vaccine candidates will need to be adaptable for alternate strains of the pathogenmuch the way current vaccines for influenza are modified to keep pace with viral evolution. New strategies for formulating and biomanufacturing such vaccines offer renewed hope for norovirus vaccine development in the near future.

Arnzen's lecture will take place in Room 220 (VCC West Building).

Charles Arntzen holds the Florence Ely Nelson Presidential Endowed Chair at Arizona State University and is a Professor at the College of Liberal Arts and Sciences, School of Life Sciences.

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Public release date: 17-Feb-2012
[ | E-mail | Share ]

Contact: Joseph Caspermeyer
Joseph.Caspermeyer@asu.edu
Arizona State University

Noroviruses are believed to make up half of all food-borne disease outbreaks in the United States, causing incapacitating (and often violent) stomach flu. These notorious human pathogens are responsible for 90 percent of epidemic nonbacterial outbreaks of gastroenteritis around the world.

On Friday, February 17, 2012 at 10:00 a.m., Charles Arntzen, ASU Regents' professor, and professor in the Center for Infectious Diseases and Vaccinology at the Biodesign Institute will deliver a lecture entitled Countdown to the Introduction of a Norovirus Vaccine. The talk will take place during the American Association for the Advancement of Science's annual meeting in Vancouver, BC.

Arntzen's lecture is part of a special topical seminar: NorovirusThe Modern Scourge of Food and Family.

The seminar title is well chosennoroviruses are extremely contagious, readily passing from person to person, particularly among those living in the closed quarters of dormitories, nursing homes, child care centers, military bases, and cruise ships. Infections can result from contact with virus particles dispersed in the air or from the ingestion of even tiny quantities of contaminated food. Further, even vigorous hand washing or the use of alcohol wipes or gels may be ineffective in combating norovirus transmission. Noroviruses can persist in a transmissible state for days or weeks even in those who are asymptomatic or are recovering from the disease.

Arntzen will speak about the prospects for a successful vaccine to prevent norovirus infection, based on Virus-Like Particles (VLPs), which are able to mimic actual noroviruses, stimulating a robust immune response, without producing disease symptoms. Due to the frequent mutation of noroviruses, vaccine candidates will need to be adaptable for alternate strains of the pathogenmuch the way current vaccines for influenza are modified to keep pace with viral evolution. New strategies for formulating and biomanufacturing such vaccines offer renewed hope for norovirus vaccine development in the near future.

Arnzen's lecture will take place in Room 220 (VCC West Building).

Charles Arntzen holds the Florence Ely Nelson Presidential Endowed Chair at Arizona State University and is a Professor at the College of Liberal Arts and Sciences, School of Life Sciences.

###

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2012-02/asu-ctt020812.php

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London Session: BOE shifts its stance and Greek tail risks increase

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You can watch our latest London video blog here with even more analysis: ?http://www.youtube.com/watch?v=muYmHYUgL6I

There are two forces working on the markets right now: 1, central banks in simulative mode and 2, fragile recoveries and tail risk from Europe. Both have been out in force today. Earlier Eurozone economic data for Q4 2011 actually surprised to the upside, GDP contracted by 0.3%, better than the 0.4% fall that was forecast.?

France's economy managed to stay above water in the last three months of 2011, while Germany didn't contract as much as expected, although Italy slipped into a technical recession after its economy contracted 0.7% in Q4 after falling 0.2% in Q3. The market took the GDP data in its stride, after all everyone in the market expected weakness at the end of 2011 and now people want to know how quick the recovery will be in 2012. What was far more interesting were reports that French car maker Peugeot had apparently approached the ECB about EUR 1bn of loans that are backed by collateral. So has the ECB has replaced the entire banking system in Europe, or what?

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We don't know if this plan by Peugeot would be accepted, but it leads one to question the integrity of the ECB's balance sheet in the wake of the LTRO programme. It also suggests that some corporates would consider cutting out the middle man (the banks) and going straight to the source of the funding - the ECB. This is another way of admitting that Europe's banking sector is up the creek without a paddle, and the even though risk may be rallying post the ECB liquidity injection, banks in Europe are still in a critical state.

On the topic of central banks and liquidity the Bank of England presented its first Inflation Report of the year. The report came after some fairly depressing labour market data. Although the unemployment rate remained steady at 8.4% (the lowest level since 1995) the claimant count rate rose more than expected in January by 6.9k, vs. 3k expected. There are now 2.67 million people unemployed in the UK, which is an increase of 48,000 over the last 3 months. Added to that wage growth remains below the rate of inflation at 2% per year, which suggests that inflation will have to fall further to stimulate consumption.

The Inflation Report was slightly less downbeat compared to the November report. Although the Bank of England still expects inflation to fall below target in the medium-term, it doesn't expect the dip below 2% to be as deep as previous. It also added that the extent to which inflation will decline and the likely pace of moderation "remain uncertain". Added to that its growth forecast was revised higher with the growth recovery pushed forward to Q1 from Q2 and Q3 previously.? Some have taken this to mean that QE is not necessarily a given. However, BOE Governor King said that more stimuli is possible and even though the Bank owns close to a third of all UK Gilts it could still buy more.

He also added that any tightening ion policy would be detrimental to the overall economic recovery in the UK and since the bulk of public sector spending cuts won't come into force until 2013 and 2014 the Bank will need to maintain an accommodative stance for some time. The pound has traded in a very tight range today. GBPUSD has traded between 1.5680 and 1.5720, it is moving with overall risk appetite although the revisions higher to the BOE's inflation and growth estimates contained in its Inflation Report is limiting pound weakness. It also helped trigger the sell-off in EURGBP after it reached 0.8400 - a harsh resistance zone where EURGBP has faltered before.

Overall, the European session has been a bitty day, with no real trend noticeable and instead fairly tight ranges are prevailing. Whether or not risk can cling on is dependent on Greece. Read more below....

Greece watch:

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Europe is still dominating the markets for the wrong reasons. After it seemed like Greece had jumped through all the hoops necessary to release its next round of bailout funds, yesterday we heard that Greece had failed at the last hurdle. The Eurogroup meeting scheduled for 1700 GMT today has been downgraded to a teleconference after the head of the Eurogroup said that Greece had failed to meet all of the demands necessary to receive the next tranche of funds.

It appears that the latest stumbling block between Greece and its next tranche of funds (read welfare) from its Eurozone peers is down to EUR 300mn of extra cuts and getting signed requests from the leaders of Greece's major political parties that they would implement the cuts agreed regardless of the outcome of April's general election. This was a bone of contention, the centre right leader, at one point last night, refused to sign the agreement. The Europeans smell a rat, and after dealing with successive failures from Greece to meet fiscal targets it is refusing to give the country the money.

The latest update is that a bridging loan could be arranged for Greece that would cover its EUR 14.5 billion bond redemption coming up on 20^th March. However, the other EUR 115.5bn of funds wouldn't be released until after elections in April.? This is not exactly the outcome that the markets were waiting for as it increases uncertainty. Markets would like to know that Greece has enough liquidity to stay afloat for the medium-term, however so far that certainty has not been forthcoming.

The reason is that no one believes Greece will need just one more bailout. What happens when its latest EUR 130 billion of funds dry up? It's unlikely that Greece will be getting more funds from irate German, Dutch and Finnish politicians who barely hide their contempt for the Med nation.

It's not just Greek-fatigue that is bolstering markets as Athens continues to flounder, it's also because since 2010 banks across the world and in Europe have been reducing their exposure to Greece and its sovereign and private sector debt. Barclays announced results last week and it now only has GBP 13 million of exposure to Greece, which is nothing for a Bank the size of Barclays. Added to that BNP Paribas, the French lender, is exposed to the tune of EUR 1.6bn, which is about EUR 3 billion lower than at the end of 2010.

Thus, the markets are not reacting as they once were to negative headlines from Athens because they are less exposed and thus less sensitive to events in Greece. This is also the case for the economic future of the Eurozone. The core is outperforming the periphery and even France, who is also trying to reduce debt, managed to export its way to growth during the last three months of 2011 expanding by a modest 0.2%, while Greece saw its economy contract 7%.

So maybe there are legs to the argument that Greece matters less to the Eurozone now than it did before, and if the European leaders can negotiate an orderly default or exit for the Eurozone then it may only have a limited impact on markets. This may be why European stocks and even peripheral bond markets have proven to be fairly resilient to the current crisis in Athens.

Best Regards,

Kathleen Brooks| Research Director UK EMEA | FOREX.com

d: +44.(0).20.7429.7924 | f: +44.(0).20.7929.2010 | M: +44 (0) 7919.411.957? | e: kbrooks@forex.com| w: www.forex.com/uk

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Disclaimer: The information and opinions in this report are for general information use only and are not intended as an offer or solicitation with respect to the purchase or sale of any currency or CFD contract. All opinions and information contained in this report are subject to change without notice. This report has been prepared without regard to the specific investment objectives, financial situation and needs of any particular recipient. Any references to historical price movements or levels is informational based on our analysis and we do not represent or warranty that any such movements or levels are likely to reoccur in the future. While the information contained herein was obtained from sources believed to be reliable, author does not guarantee its accuracy or completeness, nor does author assume any liability for any direct, indirect or consequential loss that may result from the reliance by any person upon any such information or opinions.

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Source: http://www.ibtimes.com/articles/299164/20120215/london-session-boe-shifts-stance-greek-tail.htm

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How You Can Survive Online Day Trading

von Israel Tenorio Abgelegt unter Money Beschlagwortet mit banks, day trader, dollars, gambling, hedge funds, managed accounts, Money, Mutual Funds, net worth, NYSE, riches, self employment, success, wall street, wealth 5. Februar 2012 @ 13:20

Although online trading is amongst probably the most promising forms of enterprises lately, a lot of individuals who have dared to engage into it have finished up broke. It is not for the reason that online trading just isn?t definitely capable of giving them the large income but because they?re not able to compete well in the trading industry and survive. There may very well be so many distinctive factors that a day trader could wind up out of cash in the day trading market; it may be that he doesn?t know the right strategies or that he doesn?t know the industry at all. Whether you are a day trader of your own investment or in an online stock trading business, it truly is pretty essential that you obtain a formal education regarding day trading initially ahead of getting into it.

Getting a formal or sufficient education about online trading might offer you all the knowledge and trading techniques you will need as a way to survive the business. You?ll be able to enroll in short term courses of 4 to six months becoming offered by most trading firms today. The short term classes would not just provide you with common knowledge concerning the day trading business but would also provide to enhance the trading techniques you already know. And if real estate investments in rio de janeiro apartments or homes interests you, there are courses for that also.

Trading firms have distinct approaches of educating aspiring traders to support them to develop into effective traders and rio de janeiro real estate investors. The first is naturally the selection to take short term classes of 4 to 6 months for all those who?re determined to pursue investing careers and can dedicate much more time learning how to overcome in this business.

The second may be the choice to discover from your house through online trading classes. It is a way of educating an aspiring day trader about the trading business; how it works and tips on how to survive it or perhaps master it. Online classes are a lot more handy techniques of teaching soon to be traders every thing about online stock trading, forex trading, real-estate investing and all other forms of trading business. It is also a great chance to acquire one of the reliable high frequency trading software platforms that will significantly help you in surviving the trading business. Online classes are suitable for all those who are somewhat busy with other careers while they are in the process of studying the trading business and would like a a lot more convenient time to study.

If a trader feels that he will not need to have a proper education concerning the trading business anymore, he can attend among the often held trading seminars by most trading firms to cater to those who need help surviving the business. Trading seminars contain strategies from skilled and productive traders who share their blessings of a successful trading career. The seminars are usually held for a day or a few hours in a day.

If you are amongst those people that finds it vital to pursue a trading business instead of their current jobs due to the fact they require a lot more income, you?ll want to obtain solutions to understand how o survive the business. By far the most effective way would be to acquire understanding from trading firms that have productive traders.

To incorporate a flourishing scalp trader enterprise, you must have training. This is extremely true for rio apartments for sale businesses likewise.

Source: http://www.cut-interest-rates.com/2012/02/05/how-you-can-survive-online-day-trading/

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Forex Currency Trading ? Which Of The Forex Currencies Have ...

You are here: Home / Forex / Forex Currency Trading ? Which Of The Forex Currencies Have Been Strongest In The Past 1 Year?

Source: http://www.financelearning.org/forex/forex-currency-trading-which-of-the-forex-currencies-have-been-strongest-in-the-past-1-year/

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Horse Racing Techniques ? Choosing the proper Horse ? tasty ...

Horse racing is as much as a wagering game as it is considered an activity, and horse racing tips will never be complete without tips to bet on the right horse. One would ideally want to have a system or a record database that can provide all of the necessary details over numerous parameters about a particular horse. Many people have worked to develop horse racing betting systems, a manual or software database giving racing details of every horse in the racing circuit which people can study to pick the correct equine they think would be likely to earn them bets. Such systems are present currently for the benefit of people looking for information on their own horse choices; however, there isn?t any such system that would guarantee a sure win every time.

Horse betting systems tend to be tedious to construct for the simple reason that they require an in-depth analysis of every horse and the enormous parameters that need to be incorporated to give a complete profile. For obvious reasons, itemizing more parameters will provide more details, and hence require generation of complex excel worksheets of data. As an alternative to this, software are available for the same purpose, and the numerous parameters available for use can be personalized individually to generate the best fit data according to a competition type or horse kind.

Some websites also provide horse racing data in terms of their ratings in various races; such information is available free of charge access by some web sites, while others require a regular membership for the same. The downloadable information is packaged with various variables that target providing relevant data required during horse race wagering.

Let?s have a look at some parameters used by the system to provide horse-selection information:

o The most important factor that will determine any horse?s chances of winning would have to be its own physical status. The physical statistics determine the actual fitness levels of any equine and can be readily in contrast to similar data of additional competitor horses.
o Horse racing systems often depend on financial aspects of the betting party. Hedging is a common practice used by many to deal with the doubt that is integral to horse racing. It may be described as an investment of wagering amounts in a certain way to limit loss.
o Arbitrage is another element which affects the likeliness of the horse to win or lose. It may be described in lay terms as placing a horse on the lower value, however simultaneously placing a very high value onto it at races.
o Jockey and trainer forms are also incorporated through certain betting systems when determining horse ranking.
o Drawing of lanes is sometimes considered through the betting systems as a factor that could affect a race?s outcome.

Therefore, having a reliable betting system allows its users in order to assimilate and update their database with relative ease and it is much less time consuming. The only downright downside to the system would be a fairly rigid nature of these systems, and one must bet their own selections on a daily basis else they would can easily be proven redundant.

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Source: http://tastyarticles.info/horse-racing-techniques-choosing-the-proper-horse.html

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Inspirational Self Improvement Quotes ? EraNostra

The universal truth prevails. ?There is always room for improvement?. And what?s better than improving yourself? Self improvement quotes have a bearing on our lives. Human beings need objectives so that we know where we are heading. We relentlessly seek out self-improvement and having objectives helps us realize our objectives. Every day when we get up, we know where we are heading and the craving to achieve something in life always pushes us further past any difficulty and obstruction that comes all along.

Self improvement quotes play an important part in our lives. They help us explore the different proportions of self-improvement ? its trials and troubles, its booty and purpose. A good way to start the day is by reading a few self-improvement quotes. Like our body, we need to nourish our mind with a daily dose of these quotes so that they become stronger and stronger. Eventually this can help us maintain a positive attitude in problem solving at our work place and maintain healthy relationships with others. When we feel depressed or feel like giving up on our goals, reading some of the self improvement quotes helps us remain motivated to succeed and remain inspired. This helps us in staying focused, determined and committed to being ourselves.

It is the individual responsibility of every one of us to demand the very best from ourselves. There?s no question that self improvement quotes can give what us that external flicker to retune our inner circuits. Everyone goes through ups and downs from time to time in life. It?s only natural. Everybody is prone to come under stress and pressure of day-to-day living and none, not even one of us, is invulnerable. The self improvement quotes help us deal with the challenges and obstacles we face each day, giving us strength and strengthening our thinking in our own abilities.

A regular reading of self improvement quotes can help raise our state of mind and reinstate our self-esteem. This all can happen just when we require it the most. Someone has rightly said ?Persons of high self-esteem are not driven to make them superior to others; they do not seek to prove their value by measuring themselves against a comparative standard. Their joy is being who they are, not in being better than someone else.?

Here is a small collection of selected self improvement quotes that would help in raising our confidence and could result in self-improvement:

Unless you try to do something beyond what you have mastered, you will never grow -C.R. Lawton

I?m going to get through this; I?m going to be fine. The power to do it is all in my mind ? Cindy Wagner

No one knows everything, but everyone can learn something ? Sean Gregory Derrick

Perfection does not exist, you can always do better and you can always grow ? Les Brown

The discipline of writing something down is the first step toward making it happen ? Lee Iacocca

Improve your business, your life, your relationships, your finances and your health. When you do the whole world improves ? Mark Victor Hansen

If you want further details on 2012 end of the world there is loads of information not outlined on this page, vist Author?s blog to discover more.

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This entry was posted on Saturday, February 4th, 2012 at 6:47 am and is filed under MUSIC. You can follow any responses to this entry through the RSS 2.0 feed. Both comments and pings are currently closed.

Source: http://www.eranostra.com/2012/02/04/inspirational-self-improvement-quotes/

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Inmate adds pig image to Vt. police cruiser decals

The state seal is seen on the side of a Vermont State Police cruiser Thursday, Feb. 2, 2012 in Middlesex, Vt. Some Vermont inmates have gotten the best of the state police by adding a pig to the state decal on their cruisers. One of the spots on the cow in the state crest has been changed to the shape of a pig, a derogatory term for police. The car decals are made by prisoners in St. Albans, who also make state stationary and license plates. (AP Photo/Toby Talbot)

The state seal is seen on the side of a Vermont State Police cruiser Thursday, Feb. 2, 2012 in Middlesex, Vt. Some Vermont inmates have gotten the best of the state police by adding a pig to the state decal on their cruisers. One of the spots on the cow in the state crest has been changed to the shape of a pig, a derogatory term for police. The car decals are made by prisoners in St. Albans, who also make state stationary and license plates. (AP Photo/Toby Talbot)

The state seal is seen on the side of a Vermont State Police cruiser Thursday, Feb. 2, 2012 in Middlesex, Vt. Some Vermont inmates have gotten the best of the state police by adding a pig to the state decal on their cruisers. One of the spots on the cow in the state crest has been changed to the shape of a pig, a derogatory term for police. The car decals are made by prisoners in St. Albans, who also make state stationary and license plates. (AP Photo/Toby Talbot)

BURLINGTON, Vt. (AP) ? A Vermont prison inmate who makes stationery and license plates has gotten the best of the state police by adding the image of a pig to the state decal on their cruisers.

One of the spots on the cow in the state crest has been changed to the shape of a pig, a derogatory term for police.

The 16-inch car door decals are made by prisoners in St. Albans.

Middlesex station commander Lt. Paul White tells The Burlington Free Press newspaper (http://bfpne.ws/wesdey) at least three of the altered decals are on cruisers at his barracks.

Vermont Public Safety Commissioner Keith Flynn says he learned of the altered decals Thursday and asked Corrections Commissioner Andrew Pallito to explain how it happened.

Flynn says about three dozen of the decals are on state vehicles. The state is going to remove them.

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Information from: The Burlington Free Press, http://www.burlingtonfreepress.com

Source: http://hosted2.ap.org/APDEFAULT/aa9398e6757a46fa93ed5dea7bd3729e/Article_2012-02-02-Police-Pig%20Prank/id-e24093a5c5504a79829b30b3dbc72a50

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